New HistoCyte ALK DR
Products are for professional/laboratory use only.
The ALK Dynamic Range product allows the user to determine if the ALK assay being used is sensitive enough for the use in the detection of EML4-ALK, NPM-ALK, or both.
Wild Type (WT) ALK is expressed at low levels and demonstrating it with an ALK assay is indicative of the lower limits of ALK detection. In other words, if this can be demonstrated then the assay is sensitive enough to identify ALK fusions that are often expressed at low levels, such as EML4-ALK in NSCLC. The cell line in core B of our ALK Dynamic Range product expresses WT ALK and therefore demonstrates the assay’s sensitivity.
With WT ALK, EML4-ALK and NPM-ALK positive cell lines the new ALK Analyte ControlDR allows the laboratory to control for ALK assays used in lung and lymphoma. More importantly it demonstrates the appropriate sensitivity.
*Limited samples available.
