New from ZytoVision – Bladder Cancer Quadruple Colour Probe

Products are for professional/laboratory use only.

Abacus dx is pleased to announce the release of ZytoVision’s ZytoLight® Bladder Cancer Quadruple Colour Probe. The ZytoLight® Bladder Cancer Quadruple Colour Probe is designed to detect CDKN2A (a.k.a. p16) deletions and aneuploidy of chromosomes 3, 7, and 17 in cytology specimens of tumors, e.g., in urine samples from patients with hematuria suspected of having bladder cancer (BC).

Homozygous deletion of the CDKN2A gene at 9p21.3 and polysomy of chromosome 3, 7, and/ or 17 are common abnormalities observed in urothelial cell carcinoma, all of which can be detected by FISH. Moreover, it has been shown that the detection of CDKN2A deletions and/or aneusomies of chromosomes 3, 7, and/ or 17 may be used for the surveillance of patients with a history of bladder cancer to early detect possible tumor recurrence.

FISH on cells from urine has been shown to be highly sensitive and specific for detection of tumor cells in urine. It can detect recurrence earlier than other methods like cytology, cystoscopy, or biopsy histological examination.

Please check regulatory status in your country.

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