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NKX3.1

Spotlight on NKX3.1

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NKX3.1 is a prostate-specific homeobox gene protein whose expression is predominantly localized to prostate epithelium. It acts as a transcription factor involved in prostate development. Anti-NKX3.1 labels prostate epithelium, both malignant and benign, with a nuclear visualization.

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Cell Marque: Words from our Pathologists – SATB2

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Abacus dx is pleased to share Cell Marque’s Words from our Pathologists article that discusses SATB2 (EP281).
 
Special AT-rich sequence-binding protein 2 (SATB2) is a recently described marker that functions as a nuclear matrix-associated transcription factor. SATB2 is a nuclear marker suitable for use in panels classifying carcinomas of unknown primary (CUP) origin.

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